Süt Ürünleri Tüketiminin Kolorektal Kanser Üzerine Etkisi

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Süt Ürünleri Tüketiminin Kolorektal Kanser Üzerine Etkisi

Amaç: Kanser, insanlık tarihinde bilinen en eski hastalıklardan biridir. Kolon kanserinin önlenmesi ve tedavisine yönelik son yaklaşımlar, beslenme ve kemoprevensiyon uygulamalarını içermektedir. Fonksiyonel gıdalar olarak sınıflandırılan fermente süt ürünleri bir çok hastalığın önlenmesi ve tedavisinde önemli bir yere sahiptir. Beslenmede zorunlu olarak tüketilmesi gereken gıdalar arasında yer alan süt ürünlerinin biyolojik yararları, yapısında yer alan bileşiklerden kaynaklanmaktadır. Süt ürünlerinin içerdiği kalsiyum, bütirik asit, linoleik asit, sfingomiyelin ve probiyotikler gibi koruyucu ögeler ile kanser oluşum riskini azaltabildikleri çalışmalarda ortaya koyulmuştur. Fermente süt ürünleri ile ilgili çeşitli çalışmalarda, tümör hücrelerinin gelişimini önleyebildikleri ve mutajen spektrumunu azaltabildikleri bildirilmektedir. Ayrıca meta analizleri, süt ürünleri tüketimi ve kolorektal kanser arasında ters bir korelasyon olduğunu göstermektedir. Bu derlemede, süt ürünleri tüketimi ile kolorektal kanser arasındaki ilişkinin incelenmesi amaçlanmıştır.

References

  • Akbulut, H., 2015. Kanser ve Beslenme İlişkisi. TÜBA-GIDA, Beslenme ve Kanserin Önlenmesi Sempozyumu Raporu, 33-41.
  • Atıcı, E., 2007. Tıp Tarihinde Kanser ve Lösemi. Türk Onkoloji Dergisi, 22(4):197-204.
  • Ayhan, A., 2013. Kanserin Molekuler Temelleri ve Jinekolojik Kanserlerde Önemi. Jinekolojik Onkoloji, Güneş Kitabevi, Bölüm:19, Ankara.
  • Ayyash, M., Al-Dhaheri, A.S., Al-Mahadin, S., Kizhakkayil, J. and Abushelaibi, A., 2017. In Vitro Investigation of Anticancer, Antihypertensive, Antidiabetic and Antioxidant Activities of Camel Milk Fermented with Camel Milk Probiotic: A Comparative Study with Fermented Bovine Milk. Journal Dairy Science, 101:1–12.
  • Barrubés, L., Babio, N., Becerra-Tomás, N., Rosique-Esteban, N. and Salas-Salvadó, J., 2019. Association Between Dairy Product Consumption and Colorectal Cancer Risk in Adults: A Systematic Review and Meta-Analysis of Epidemiologic Studies. Advances in Nutrition, 10:190-211.
  • Barrubés, L., Babio, N., Mena-Sánchez, G., Toledo, E., Ramírez-Sabio, J.B., Estruch, R., Ros, E., Fitó, M., Arós, F., Fiol, M., Santos-Lozano, J. M., Serra-Majem, L., Pintó, X., Martínez-González, M. Á., Sorlí, Josep, J. and Salas-Salvadó, B., 2018. Dairy Product Consumption and Risk of Colorectal Cancer in an Older Mediterranean Population at High Cardiovascular Risk. International Journal Cancer, 15;143(6):1356-1366.
  • Baykara, O., 2016. Kanser Tedavisinde Güncel Yaklaşımlar. Balıkesir Sağlık Bilimleri Dergisi, 5(3).
  • Blackadar, C.B., 2016. Historical Review of the Causes of Cancer. World Journal of Clinical Oncology, 10; 7(1):54-86.
  • Centelles, J.J., 2012. General Aspects of Colorectal Cancer. ISRN Oncology, 1-1.
  • Çevik, G., Nursal, A.F. ve Yiğit, S., 2016. Epigenetik ve Kanser. Turkiye Klinikleri J Radiat Oncol-Special Topics, 2(1);45-51
  • Davoodi, H., Esmaeili, S. and Mortazavian, A.M., 2013. Effects of Milk and Milk Products Consumption on Cancer: A Review. Comprehensive Reviews in Food Science and Food Safety, 12;3, 249-264.
  • Fitzmaurice, C., Dicker, D., Pain, A., Hamavid, H., Moradi-Lakeh, M., MacIntyre M. F., Allen, C., Hansen, G., Woodbrook, R., Wolfe, C., Hamadeh, R., Moore, A., Werdecker, A., Gessner, B., Te Ao, B., Mc Mahon, B., Karimkhani, C., Yu C., Cooke, G., Schwebel, D., Carpenter, D., Pereira, D., Nash, D., Kazi, D., Leo, D. D., Plass, D., at all. and Naghavi, M., 2015. The Global Burden of Cancer, 2013. Jama Oncology, 1(4):505-527.
  • Golemis, E.A., Scheet, P., Beck, T.N., Scolnick, E.M, Hunter, D.J, Hawk, E. and Hopkins, N., 2018. Molecular Mechanisms of the Preventable Causes of Cancer in the United States. Genes & Development, 32 (13-14): 868–902.
  • Granados-Romero, J., Valderrama-Treviño, A., Contreras-Flores, E., Barrera-Mera, B., Enríquez, M., Uriarte-Ruíz, K., Ceballos-Villalba, J., Estrada-Mata, A., Rodríguez, C. and Arauz-Peña, G., 2017. Colorectal Cancer: A Review. International Journal of Research in Medical Sciences, 5(11):4667.
  • Gürel, Ç., Nursal, A.F. and Yiğit, S., 2016. Epigenetik ve Kanser. Turkiye Klinikleri J Radiat Oncol-Special Topics, 2(1):45-51.
  • Hatmal, M., Nuirat, A., Zihlif, M. and Mutasem, O., 2018. Exploring The Influence of Culture Conditions on Kefir’s Anticancer Properties. Journal of Dairy Science, 101(5):3771-3777.
  • Hawk, E., Limburg, P. and Viner, J., 2002. Epidemiology and Prevention of Colorectal Cancer. Surgical Clinics of North America, 82(5):905-941.
  • Hill, C., Guarner, F., Reid, G., Gibson, G.R., Merenstein, D.J., Pot, B., Morelli, L., Canani, R.B., Flint, H.J., Salminen, S., Calder, P.C. and Sanders, M.E., 2014. The International Scientific Association for Probiotics and Prebiotics Consensus Statement on the Scope and Appropriate Use of the Term Probiotic. Nature Reviews Gastroenterology & Hepatology, 11, 506–514
  • Jemal, A., Siegel, R., Xu, J. and Ward, E., 2010. Cancer Statistics. CA: A Cancer Journal for Clinicians, 60(5):277-300.
  • Kahraman, M. and Karahan, A., 2018. Probiyotiklerin Tümör Baskılayıcı Etkileri. Türk Hijyen ve Deneysel Biyoloji Dergisi, 75(4): 421-442.
  • Kinany, K.E., Deoula, M.M.S., Hatime, Z., Boudouaya, H.A., Huybrechts, I., Asri, A.E., Benider, A.,·Ahallat, M., Afqir, S., Mellas, N., Khouchani, M. and Rhazi, K.E., 2020. Consumption of Modern and Traditional Moroccan Dairy Products and Colorectal Cancer Risk: a large Case Control Study. European Journal of Nutrition, 59, 953–963.
  • Kıray, E. and Kariptaş, E., 2015. Probiyotikler, Prebiyotikler ve Sinbiyotiklerin Kolorektal Kanser İlişkisi. Elektronik Mikrobiyoloji Dergisi, 13(1): 28-46.
  • Kroenke, C.H., Kwan, M.L., Sweeney, C., Castillo, A. and Caan, B.J., 2013. High- and Low-Fat Dairy Intake, Recurrence, and Mortality after Breast Cancer Diagnosis. Journal of the National Cancer Institute, 105(9), 616-623.
  • Kuipers, E., Grady, W., Lieberman, D., Seufferlein, T., Sung J., Boelens, P., Cornelis, J., De Velde, V. and Watanabe, T., 2015. Colorectal Cancer. Nature Reviews Disease Primers, 5,1:15065.
  • Laakkonen, A. and Pukkala, E., 2008. Cancer Incidence among Finnish Farmers, 1995–2005. Scand J Work Environ Health, 34(1):73–79.
  • Lamichhane, P., Maiolini, M., Alnafoosi, O., Hussein, S., Alnafoosi, H., Umbela, S., Richardson, T., Alla, N., Lamichhane, N., Subhadra, B., and Deshmukh, R. R., 2020. Colorectal Cancer and Probiotics: Are Bugs Really Drugs? Cancers, 12(5), 1162.
  • Larsson, S., Bergkvist, L., Rutegård, J., Giovannucci, E. and A Wolk, A., 2006. Calcium and Dairy Food Intakes are Inversely Associated with Colorectal Cancer Risk in the Cohort of Swedish Men. The American Journal of Clinical Nutrition. 83(3):667-673.
  • Marshall, N., 2004. Therapeutic Applications of whey Protein. Alternative Medicine Review:A journal of Clinical Therapeutic, 9(2):136–156.
  • Mc Cann, S., Ip, C., Ip, M., Mc Guire, M., Muti, P., Edge, S., Trevisan, M. and Freudenheim, J., 2004. Dietary Intake of Conjugated Linoleic Acids and Risk of Premenopausal and Postmenopausal Breast Cancer Western New York Exposures and Breast Cancer Study (WEB Study). Cancer Epidemiology Biomarkers and Prevention, 13(9):1480-1484.
  • Mumcu, H., 2014. Kırk Yaş ve Üzeri Kanser Tanısı Almamış Bireylerin Kansere İlişkin Bilgi, Tutum ve Davranışları. Doktora Tezi. Erciyes Üniversitesi Sağlık Bilimleri Enstitüsü, Kayseri.
  • Murphy, N., Norat, T., Ferrari, P., Jenab, M., Bueno-de-Mesquita, B., Skeie, G. and Olsen, A., 2013. Consumption of Dairy Products and Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC). PLoS One, 8(9): 727-715.
  • Nyström, M. and Mutanen, M., 2009. Diet and Epigenetics in Colon Cancer. World Journal of Gastroenterology, 15, 257–263.
  • O’Sullivan, T. A., Hafekost, K., Mitrou, F. and Lawrence, D., 2013. Food Sources of Saturated Fat and the Association with Mortality: A Meta-Analysis. American Journal of Public Health (AJPH), 31-42.
  • Okyay, P., 2013. Kolorektal Kanser Epidemiyolojisi. Turkiye Klinikleri Tıbbi Onkoloji, 6(3):1-5.
  • Pala, V., Sieri, S., Berrino, F., Vineis, P., Sacerdote, C., Palli, D., Masala, G., Panico, S., Mattiello, A., Tumino, R., Giurdanella, M., Agnoli, C., Grioni, S.and Krogh, V., 2011. Yogurt Consumption and Risk of Colorectal Cancer in the Italian European Prospective Investigation into Cancer and Nutrition cohort. International Journal of Cancer, 129(11):2712-2719.
  • Parodi, P., 2005. Dairy Product Consumption and the Risk of Breast Cancer. Journal of the American College of Nutrition, 24(6):556-568.
  • Pavlopoulou, A., Spandidos D. and Michalopoulos, I., 2015. Human Cancer Databases (Review). OncologyReports, 33(1):3-18.
  • Pecorino, L., 2012. Molecular Biology of Cancer. Mechanisms, Targets, and Therapeutics Chapter 1, Fourth Edition, Oxford University Press, P:1-5.
  • Pettersson, A., Kasperzyk, J.L., Kenfield, S.A., Richman E.L., Chan J.M., Willett W.C., Stampfer, M.J., Mucci, L.A. and Giovannucci E.L., 2012. Milk and Dairy Consumption among Men with Prostate Cancer and Risk of Metastases and Prostate Cancer Death. Cancer Epıdemıology, Bıomarkers & Preventıon, 11-1004.
  • Rennert, G., Rennert, H.S., Gronich, N., Pinchev, M. and Gruber, S.B., 2020. Use of Metformin and Risk of Breast and Colorectal Cancer. Diabetes Research and Clinical Practice, 165:108232.
  • Rodríguez-Alcalá L.M., Fontecha, J., 2007. Hot Topic: Fatty Acid and Conjugated Linoleic Acid (CLA) Isomer Composition of Commercial Clafortified Dairy Products: Evaluation After Processing and Storage. Journal of Dairy Science, 90:2083–2090.
  • Siegel, R., Naishadham, D. and Jemal, A., 2012. Cancer Statistics. CA: a Cancer Journal for Clinicians, 62(1):10-29.
  • Şireli, U. T., 2015. Hepimiz Sütten Özür Dileyeceğiz. Infovet Dergisi, 134,56-71.
  • Um, C., Prizment, A., Hong, C., Lazovich, D. and Bostick, R., 2019. Associations of Calcium, Vitamin D and Dairy Product Intakes with Colorectal Cancer Risk Among Older Women: The Iowa Women’s Health Study. Nutritional Cancer, 71(5):739-748.
  • Weingarten, M. A., Trestioreanu, A. Z. and Yaphe, J., 2010. Dietary Calcium Supplementation for Preventing Colorectal Cancer and Adenomatous Polyps (Review). Cochrane Database of Systematic Reviews, 9.
  • Woude, G.F.V. and Klein, G., 2009. Advances in Cancer Research. Academic Press, 1(104), 1-215.